266 Risk of opportunistic, viral, and hospitalized infections in atopic dermatitis

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Atopic Dermatitis Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis

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Endogenous antimicrobial peptides and skin infections in atopic dermatitis.

BACKGROUND The innate immune system of human skin contains antimicrobial peptides known as cathelicidins (LL-37) and beta-defensins. In normal skin these peptides are negligible, but they accumulate in skin affected by inflammatory diseases such as psoriasis. We compared the levels of expression of LL-37 and human beta-defensin 2 (HBD-2) in inflamed skin from patients with atopic dermatitis and...

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Atopic dermatitis: global epidemiology and risk factors.

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Abstract Background and objective: Being exposed to different allergens, followed by the production of specific IgE, has an important role in causing atopic dermatitis, recognizing the allergens and applying immunotherapy for treatment. We aimed to determine the frequency of common allergens in the patients suffering from atopic dermatitis. Material and Methods: In this descriptive- anal...

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2021

ISSN: ['1523-1747', '0022-202X']

DOI: https://doi.org/10.1016/j.jid.2021.02.288